KGK Synergize

In 2007, KGK Science, Inc., an independent laboratory in Canada, examined the effects of POLY-MVA on 8 cancer cell lines.

These lines included:
1) Skin melanoma, human (SKMel-5)
2) Liver, hepatocellular carcinoma, human (Hep G2)
3) Lung, malignant melanoma, human (Malme-3M)
4) Mammary gland, ductal carcinoma, human (MDA-MB 435)
5) Prostate, left supraclavicular lymph node carcinoma, human (LNCaP)
6) Colon, colorectal adenocarcinoma, human (HT-29)
7) Human brain, glioblastoma; astrocytoma (U87)
8) Glioblastoma (HT-80)

POLY-MVA was administered at 3 different dosages and the number of cells was examined after 24, 48 and 72 hours following initial application. POLY-MVA was effective, to varying degrees, on the entire group of cell lines tested (melanoma, liver, lung, breast, prostate, colon, astrocytoma and glioblastoma).

The varying effectiveness appears to be a consequence of the particular cell lines used and their associated degree of anaplasia.

Poly MVA causes significant cell death after 48 Hours of exposure 
per mL.  SHAPE  \* MERGEFORMAT CPM

Garnett McKeen In vitro Cancer Assays:
Garnett McKeen Laboratory Inc. (GML) chose to mimic the National Cancer Institute’s (NCI) cell screening protocol.

The following cell lines were selected from the NCI repository:

MCF-7 (breast adenocarcinoma), and A549 (lung non-small cell adenocarcinoma).

The data below represents the completion of the Breast Cancer (MCF-7), Ovarian Cancer (OVCAR-5) and Lung Carcinoma (A549) assay.

We have also completed assays using stage IV glioblastoma multiforme (H-80) and astrocytoma (H-4) brain tumor lines.

As noted below, all of the studies demonstrated significant cell death.

CANCER CELL DEATH RATE IN 5 CELL LINES After 48 hours of exposure

Lung Cancer (Non-Small Cell Carcinoma)

83.8% Lung Cancer Cell Death after 48 Hours